Preface| Volume 37, ISSUE 1, Pxiii-xvi, February 2023

Escalation, De-escalation, Adaptation, Speciation, Customization: The New Approaches to Breast Cancer

      Figure thumbnail fx1
      Harold J. Burstein, MD, PhD, Editor
      Our approaches to breast cancer treatment have undergone a radical transformation over the past 20 years. Catalysts for this transformation include advances in tumor genetics and genomics that have allowed us to effectively define unique subsets or species of breast cancers, both for research purposes and for tailoring individual treatment plans; the development of far more effective targeted therapies, most notably HER2-directed targeted therapies, that have altered the natural history of the disease; and the integration of true multidisciplinary care, where there is an adaptive interplay between stage, local-regional treatments (surgery and radiation), and the likelihood of response to systemic therapy.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.


      Subscribe to Hematology/Oncology Clinics
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect