Acute Myeloid Leukemia

The evolution of acute myeloid leukemia (AML) classification reflects greater understanding of the AML pathogenesis. The 2008 World Health Organization classification incorporated cytogenetic and molecular genetic findings and introduced important prognostic correlations. In this article, the authors discuss the different types of AML and their diagnoses.

Keywords: Acute myeloid leukemia, WHO 2008 classification, Recurrent genetic abnormalities, Myelodysplasia-related changes, Therapy-related myeloid neoplasms

a Department of Pathology, Stanford University Medical Center, 300 Pasteur Drive, Lane Building, Room 235, Stanford, CA 94305, USA

b Stanford University Medical Center, 300 Pasteur Drive, H1507C- M/C5627, Stanford, CA 94305-5627, USA

Corresponding author.

PII: S0889-8588(09)00079-3

doi:10.1016/j.hoc.2009.04.003

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