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Volume 19, Issue 1, Pages 87-117 (February 2005)


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Antiplatelet Agents: Current Drugs and Future Trends

Harry L. Messmore Jr, MDabCorresponding Author Informationemail address, Walter P. Jeske, PhDc, William Wehrmacher, MDd, Erwin Coyne, PhDa, Sohrab Mobarhan, MDe, Leslie Cho, MDf, Fred S. Leya, MDf, John F. Moran, MDf

Antiplatelet drugs in clinical use are discussed in terms of their mechanisms of action and the relevancy of that to the physiology of platelets and the pathophysiology of arterial thrombosis. Current clinical usage is outlined in detail for each drug. Experimental antiplatelet drugs also are discussed.

a Hines Veteran's Affairs Hospital, Hines, IL 60141, USA

b Loyola University Stritch School of Medicine, Cancer Center, Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA

c Loyola University Stritch School of Medicine, Cardiovascular Institute, Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA

d Loyola University Stritch School of Medicine, Department of Physiology, Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA

e Loyola University Stritch School of Medicine, Department of Gastroenterology, Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA

f Loyola University Stritch School of Medicine, Division of Cardiology, Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA

Corresponding Author InformationCorresponding author. Hines Veteran's Affairs Hospital, Hines, IL 60141

PII: S0889-8588(04)00113-3

doi:10.1016/j.hoc.2004.09.004


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