Breast cancer: the role of angiogenesis and antiangiogenic therapy
Angiogenesis plays a role in breast cancer development. Preclinical and clinical evidence is reviewed. Development of targeted antiangiogenic agents provides new challenges to clinical trial design. Current antiangiogenic therapy with traditional agents and novel agents are classified and reviewed.
aDivision of Hematology and Medical Oncology, Indiana University, 535 Barnhill Drive, RT-473, Indianapolis, IN 46202, USA
bDivision of Hematology and Medical Oncology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97201-3098, USA
Corresponding author
This work was supported in part by the Breast Cancer Research Foundation.
ABSTRACT